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In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This sheet talks about whether exposure to sertraline may increase the risk for birth defects over that background risk.

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This information should not take the place of medical care and advice from your health care provider.

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Sertraline (trade names Zoloft and others) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline is primarily prescribed for major depressive disorder in adult outpatients as well as obsessive-compulsive disorder, panic disorder, and social anxiety disorder, in both adults and children. Differences with other newer antidepressants are subtle and mostly confined to side effects.

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Zoloft is the brand name of sertraline, an antidepressant used to treat major depressive disorders.

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